Your Trusted Partner In Women’s Health

FOR US HEALTHCARE PROFESSIONALS

Your Trusted Partner In Women’s Health

Join our growing network of healthcare professionals giving women a non-hormonal option for perimenopause, menopause and bladder health.

Become a Partner

FOR US HEALTHCARE PROFESSIONALS

Your Trusted Partner In Women’s Health

Join our growing network of healthcare professionals giving women a non-hormonal option for perimenopause, menopause and bladder health.

Become a Partner

Recommended by ISGE

27 studies on Pure CyTonin®

90+ Years of Pharmaceutical Expertise

Made in NSF & GMP Certified Facilities

the key ingredient

Patented Pure CyTonin®

A kilo of Swedish blossoms yields just a few grams of pollen extract. Every capsule is then made in France by UPSA, in NSF- and GMP-certified facilities backed by 90+ years of pharmaceutical expertise.

Collected

Pollen is gathered from flowers grown in Sweden.

Shell removed

Each grain's tough outer shell, where the allergens sit, is taken away.

Purified

The cytoplasm inside is concentrated into Pure CyTonin®.

68%

reduction in hot flashes

62%

reduction in night sweats

56%

reduction in fatigue and tiredness

60%

reduction in irritability

50%

reduction in sleep problems

Results from double-blind, placebo-controlled clinical studies in perimenopausal and menopausal women over 8 to 12 weeks of daily use. ¹

NON-HORMONAL & NON-ESTROGENIC

Contains no hormones or phytoestrogens. In lab tests, it showed no estrogen-like activity.

THE SCIENTIFIC EVIDENCE

Clinical studies aren't optional. It’s our standard.

A deep dive into how Pure CyTonin® performs when put to the test.

Controlled trial

Pollen extract versus placebo for hot flashes and quality of life

Winther et al. · Climacteric · 2005 · n=64 · 12 weeks

Randomized, placebo-controlled, parallel-group study in 64 menopausal women. After 12 weeks of daily use, 65% of women taking the pollen extract had fewer hot flashes, compared with 38% on placebo (p < 0.006). Hormone levels didn't differ between the groups, and the authors reported improved quality of life.

Full study record

ACTIVE INGREDIENTS: PI and GC Fem pollen extracts, the same extracts used in Pure CyTonin®
DESIGN: Randomized, placebo-controlled, parallel-group
DEMOGRAPHIC: Menopausal women
DURATION: 12 weeks
SAMPLE SIZE AND DOSE: 64 women · 2 tablets a day
RESULTS: Fewer hot flashes in 65% of women on pollen extract vs 38% on placebo (p < 0.006). No differences in FSH, estrogen, SHBG or testosterone between groups. Improved quality of life reported.
CITATION: Winther K, Rein E, Hedman C. Femal, a herbal remedy made from pollen extracts, reduces hot flushes and improves quality of life in menopausal women: a randomized, placebo-controlled, parallel study. Climacteric. 2005;8(2):162–170. doi:10.1080/13697130500117987

Controlled trial

PureCyTonin® for hot flashes in breast cancer survivors

Gynecological Endocrinology · 2024 · n = 39 · 3 months

Multicenter, randomized, double-blind, placebo-controlled trial in 39 breast cancer survivors in Italy. After 3 months, women taking Pure CyTonin® had significantly fewer hot flashes than when they started (p = 0.02), and the extract was well tolerated.

Full study record

ACTIVE INGREDIENTS: Pure CyTonin® (purified and specific cytoplasmic pollen extract)
DESIGN: Prospective, multicenter, randomized, double-blind, placebo-controlled
DEMOGRAPHIC: Breast cancer survivors with hot flashes, in Italy
Sample size AND DOSE: 39 women randomized (19 Pure CyTonin®, 20 placebo) · [dose: to complete]
Duration: 3 months
Results: Measured with a daily hot flash diary, the Menopause Rating Scale (MRS), the Pittsburgh Sleep Quality Index (PSQI) and visual analog scales (VAS). Compared with baseline:
Pure CyTonin® group: fewer hot flashes at 3 months (p = 0.02, daily diary)
VAS ratings at 3 months: improved hot flash intensity (p = 0.04), sweating (p = 0.02), irritability (p = 0.03) and fatigue (p = 0.04)
Pure CyTonin® group: better total MRS score at 1 month (p = 0.03)
Well tolerated
Citation: Bounous VE, Cipullo I, D'Alonzo M, Martella S, Franchi D, Villa P, Biglia N, Ferrero A. A prospective, multicenter, randomized, double-blind placebo-controlled trial on purified and specific Cytoplasmic pollen extract for hot flashes in breast cancer survivors. Gynecol Endocrinol. 2024 Dec;40(1):2334796. doi: 10.1080/09513590.2024.2334796. Epub 2024 May 17. PMID: 38760920.

FORMULATION QUALITY AND SAFETY

Standardized, purified and fully disclosed

Every batch of pollen extract is checked by HPLC and gas chromatography. Every capsule is made in France by UPSA, in NSF- and GMP-certified facilities backed by 90+ years of pharmaceutical expertise.

FEM PERIMENO

Other ingredients: Microcrystalline Cellulose (to blend), Potato Starch, Magnesium Stearate (to avoid clumping). Capsule: Hydroxypropyl Methylcellulose.

FEM MENO

Other ingredients: Potato Starch, Microcrystalline Cellulose (to blend), Magnesium Stearate (to avoid clumping). Capsule: Hydroxypropyl methylcellulose.

FEM UROVITAL

Other ingredients: Potato Starch, Magnesium Stearate (to avoid clumping), Microcrystalline Cellulose (to blend). Capsule: Hydroxypropyl methylcellulose.

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